Biologic Chromoendoscopy – The Eye Beats Artificial Intelligence

By Klaus Mönkemüller, MD, PhD, FASGE, FJGES 

Professor of Medicine, Virginia Tech Carilion School of Medicine, Roanoke, USA 

Natural or Biologic Chromoendoscopy for Detection of Colorectal Polyps 

Endoscopic detection and resection of colorectal polyps is the key determinant for eventual prevention of colorectal cancer. Whereas visualization of sessile and pedunculated colon polyps is relatively straightforward and easy, finding flat or sessile serrated lesions is more challenging, more so for visual aid systems using artificial intelligence, or traditional virtual or dye-based chromoendoscopy techniques, as these lesions tend to secrete mucus or accumulate debris, or stool on their surface (Figure 1).